Dearomative [4+2] Cycloaddition of Oxindole‐Embedded <i>ortho</i>‐Quinone Methides with 2,5‐Dialkylfurans

Abstract

Abstract 2,5‐Dialkylfurans were facilely converted to pharmaceutically significant spiro[chroman‐4,3′‐oxindole] scaffolds via an organocatalytic dearomative [4+2] cycloaddition with oxindole‐embedded ortho ‐quinone methides. This method featured mild reaction conditions, simple operation, good yields, and excellent diastereoselectivities. magnified image