GLI1 overexpression promotes gastric cancer cell proliferation and migration and induces drug resistance by combining with the AKT-mTOR pathway

References

Page 1

	Year	Citations
Cancer statistics, 2016 Rebecca L. Siegel, Kimberly D. Miller, Ahmedin Jemal CA A Cancer Journal for Clinicians	2016	16.1K
Combination Therapy With Infliximab and Azathioprine Is Superior to Monotherapy With Either Agent in Ulcerative Colitis Remo Panaccione, Subrata Ghosh, Stephen Middleton, Gastroenterology InflammationChronic Inflammatory DiseasesAnti-inflammatoryAutoimmune DiseaseEither Agent	2013	947
Melanomas require HEDGEHOG-GLI signaling regulated by interactions between GLI1 and the RAS-MEK/AKT pathways Barbara Stecca, Christophe Mas, Virginie Clément, Proceedings of the National Academy of Sciences Signaling PathwayCell RegulationSonic HedgehogHedgehog-gli SignalingMedicine	2007	525
Sonic Hedgehog Pathway Promotes Metastasis and Lymphangiogenesis via Activation of Akt, EMT, and MMP-9 Pathway in Gastric Cancer Young A. Yoo, Myoung Hee Kang, Hyun Joo Lee, Cancer Research	2011	351
The Crosstalk of mTOR/S6K1 and Hedgehog Pathways Yan Wang, Qingqing Ding, Chia-Jui Yen, Cancer Cell Signal TransductionHedgehog PathwaysCell DivisionSignaling PathwayIntercellular Communication	2012	348
The critical role of AMPK in driving Akt activation under stress, tumorigenesis and drug resistance Fei Han, Chien‐Feng Li, Zhen Cai, Nature Communications	2018	181
The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation Hiba Ahmad Zahreddine, Biljana Culjkovic‐Kraljacic, Sarit Assouline, Nature MedicineGlycobiologyPharmacologyCell BiologyDrug Discovery	2014	180
AMP-Activated Protein Kinase Directly Phosphorylates and Destabilizes Hedgehog Pathway Transcription Factor GLI1 in Medulloblastoma Yen-Hsing Li, Jia Lin Luo, Yung‐Yi C. Mosley, Cell Reports	2015	102
Non-canonical GLI1/2 activation by PI3K/AKT signaling in renal cell carcinoma: A novel potential therapeutic target Jiancheng Zhou, Guodong Zhu, Jun Huang, Cancer Letters UrologyGenitourinary CancerMedicineReceptor Tyrosine KinaseRenal Cell Carcinoma	2015	102
A critical role of autocrine sonic hedgehog signaling in human CD138+ myeloma cell survival and drug resistance Zhiqiang Liu, Jingda Xu, Jin He, Blood	2014	98

Page 1