Spinal cord injury by clip-compression induces anxiety and depression-like behaviours in female rats: The role of the inflammatory response

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.7K citations

Experimental Psychopathology, Closed Arm Entries, Stress Hormone +11

A Sensitive and Reliable Locomotor Rating Scale for Open Field Testing in Rats

D. Michele Basso, Michael S. Beattie, Jacqueline C. Bresnahan · Journal of Neurotrauma · 1995 · 4.5K citations

Gait Analysis, Physical Activity, Motor Control +25

Behavioral despair in mice: a primary screening test for antidepressants.

Porsolt Rd, Aurélie Bertin, M Jalfre · PubMed · 1977 · 3.3K citations

Depressed State, Psychopharmacology, Mental Health +19

The use of the elevated plus maze as an assay of anxiety-related behavior in rodents

Alicia A. Walf, Cheryl A. Frye · Nature Protocols · 2007 · 2.9K citations · Full text

Experimental Psychopathology, Behavioral Sciences, Stress Hormone +9

Serotonin receptor 1A knockout: An animal model of anxiety-related disorder

Sylvie Ramboz, Ronald S. Oosting, Djamel Aït Amara et al. · Proceedings of the National Academy of Sciences · 1998 · 810 citations · Full text

Individual Serotonin, Neurotransmitter, Affective Neuroscience +18