One-pot synthesis of chiral β-hydroxysulfones from alkynes <i>via</i> aerobic oxysulfonylation and asymmetric reduction in MeOH/H<sub>2</sub>O

Peng Cui, Qixing Liu, Juan Wang, Huan Liu, Haifeng Zhou

Green Chemistry · 2019 · 36 citations · 45 references

Concepts

Abstract

A highly enantioselective synthesis of β-hydroxysulfones from inexpensive and readily available alkynes <italic>via</italic> a consecutive one-pot reaction in MeOH/H<sub>2</sub>O under mild conditions is described.

References

45