A universal photoelectrochemical biosensor for dual microRNA detection based on two CdTe nanocomposites

Abstract

NCs through covalent bonding respectively. With the competitive hybridization reaction between target miRNAs and the complementary DNA (cDNA), concentrations of miRNA141 and miRNA21 may be sensitively quantified by the respective photocurrent change. Compared with traditional PEC biosensors, this design didn't require any additional equipment and can provide a higher detection efficiency, which has a good universality and expansibility for the fabrication of multiplex PEC assays.