Clinical Utility of Cerebrospinal Fluid Cell-Free DNA as Liquid Biopsy for Leptomeningeal Metastases in ALK-Rearranged NSCLC

Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA

Muhammed Murtaza, Sarah‐Jane Dawson, Dana W.Y. Tsui et al. · Nature · 2013 · 1.6K citations

Medicine, Molecular Biology, Oncology +17

Non-Invasive Analysis of Acquired Resistance to Cancer Therapy By Sequencing of Plasma Dna

Annals of Oncology · 2014 · 1.2K citations · Full text

Medicine, Molecular Biology, Oncology +17

Cerebrospinal fluid-derived circulating tumour DNA better represents the genomic alterations of brain tumours than plasma

Leticia De Mattos‐Arruda, Regina Mayor, Charlotte K.Y. Ng et al. · Nature Communications · 2015 · 858 citations · Full text

Medicine, Molecular Genetics, Oncology +17

Detection and Dynamic Changes of <i>EGFR</i> Mutations from Circulating Tumor DNA as a Predictor of Survival Outcomes in NSCLC Patients Treated with First-line Intercalated Erlotinib and Chemotherapy

Tony Mok, Yi‐Long Wu, Jin Soo Lee et al. · Clinical Cancer Research · 2015 · 469 citations

Medicine, Oncology, Pharmacology +17

Activity and safety of brigatinib in ALK-rearranged non-small-cell lung cancer and other malignancies: a single-arm, open-label, phase 1/2 trial

Scott Gettinger, Lyudmila Bazhenova, Corey J. Langer et al. · The Lancet Oncology · 2016 · 350 citations

Medicine, Oncology, Pharmacology +14