Concepedia

Degradation of Cytosine Radical Cations in 2′-Deoxycytidine and in i-Motif DNA: Hydrogen-Bonding Guided Pathways

Yinghui Wang, Hongmei Zhao, Chunfan Yang, Jialong Jie, Xiaojuan Dai, Qian Zhou, Kunhui Liu, Di Song, Hongmei Su

Journal of the American Chemical Society · 2019 · 28 citations · 43 references

DOI

Concepts

Abstract

. The C radicals in i-motif thus retain more cation character, and are mainly subject to hydration leading to lesion products that can induce disruption of i-motif structure and affect its critical roles in gene-regulation.

References

43

A tetrameric DNA structure with protonated cytosine-cytosine base pairs

Kalle Gehring, Jean‐Louis Leroy, M. Guéron · Nature · 1993 · 1.2K citations

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Direct observation of hole transfer through DNA by hopping between adenine bases and by tunnelling

Bernd Giese, Jérôme Amaudrut, Anne-Kathrin Köhler et al. · Nature · 2001 · 824 citations

, , +5

I-motif DNA structures are formed in the nuclei of human cells

Mahdi Zeraati, D.B. Langley, Peter Schofield et al. · Nature Chemistry · 2018 · 564 citations

, , +14

i-Motif DNA: structural features and significance to cell biology

Hala Abou Assi, Miguel Garavís, Carlos González et al. · Nucleic Acids Research · 2018 · 425 citations · Full text

, , +17

Oxidized, deaminated cytosines are a source of C → T transitions <i>in vivo</i>

Deborah A. Kreutzer, John M. Essigmann · Proceedings of the National Academy of Sciences · 1998 · 315 citations · Full text

, , +15