CD4<sup>+</sup> CD25<sup>+</sup> regulatory T cells promote hepatocellular carcinoma invasion via TGF-β1-induced epithelial–mesenchymal transition - Concepedia

Concepedia

Publication | Open Access

CD4<sup>+</sup> CD25<sup>+</sup> regulatory T cells promote hepatocellular carcinoma invasion via TGF-&beta;1-induced epithelial&ndash;mesenchymal transition

DOI Full Paper Access

56

Citations

15

References

2018

Year

Chunying Shi, Ying Chen, Yaodong Chen, Yuchuan Yang, Bing Wang, Jiping Qi

OncoTargets and Therapy

Abstract

Tregs could promote the invasion and migration of Hepa1-6 cells, which are possibly maintained by TGF-β1-induced EMT. This study showed that the development of therapeutic strategies against TGF-β1 pathway is valuable in HCC therapy.

References

	Year	Citations

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