Functional polymorphisms of the APOA1/C3/A4/A5-ZPR1-BUD13 gene cluster are associated with dyslipidemia in a sex-specific pattern

Abstract

SNPs in the <i>APOA1/C3/A4/A5-ZPR1-BUD13</i> gene cluster were associated with dyslipidemia. Furthermore, the association of <i>APOA1</i> rs5072 in this gene cluster with dyslipidemia differed between genders; thus, additional studies are needed to confirm this conclusion, and the mechanisms underlying these results warrant further exploration.