Roflumilast ameliorates cognitive impairment in APP/PS1 mice via cAMP/CREB/BDNF signaling and anti-neuroinflammatory effects

Dementia: a global health priority - highlights from an ADI and World Health Organization report

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Medicine, Health Policy, Neurology +17

Quantitative comparison of phosphodiesterase mRNA distribution in human brain and peripheral tissues

Viktor Lakics, Eric Karran, Frank Boess · Neuropharmacology · 2010 · 464 citations

Life Sciences, Molecular Biology, Neuroscience +8

Persistent improvement in synaptic and cognitive functions in an Alzheimer mouse model after rolipram treatment

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Life Sciences, Neuroscience, Pharmacology +17

Amyloid-β Peptide Inhibits Activation of the Nitric Oxide/cGMP/cAMP-Responsive Element-Binding Protein Pathway during Hippocampal Synaptic Plasticity

Daniela Puzzo, Ottavio V. Vitolo, Fabrizio Trinchese et al. · Journal of Neuroscience · 2005 · 243 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Reversal of long-term dendritic spine alterations in Alzheimer disease models

Donna L. Smith, Julio Pozueta, Bing Gong et al. · Proceedings of the National Academy of Sciences · 2009 · 235 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17