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Burden of Streptococcus pneumoniae Sepsis in Children After Introduction of Pneumococcal Conjugate Vaccines: A Prospective Population-based Cohort Study

Sandra Asner, Philipp Agyeman, Eugénie Gradoux, Klara M. Posfay‐Barbe, Ulrich Heininger, Éric Giannoni, Pierre Alex Crisinel, Martin Stocker, Sara Bernhard‐Stirnemann, Anita Niederer-Loher,

Clinical Infectious Diseases · 2018 · 28 citations · 18 references

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Abstract

The incidence of pneumococcal sepsis in children shortly after introduction of PCV-13 remained substantial. Meningitis mostly due to non-vaccine serotypes and disease caused by serotype 3 represented significant predictors of severity.

References

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Effect of use of 13-valent pneumococcal conjugate vaccine in children on invasive pneumococcal disease in children and adults in the USA: analysis of multisite, population-based surveillance

Matthew R. Moore, Ruth Link‐Gelles, William Schaffner et al. · The Lancet Infectious Diseases · 2015 · 716 citations · Full text

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