Concepedia

Publication | Open Access

Protein Phosphatase 2A Regulates Cardiac Na <sup>+</sup> Channels

DOIFull Paper Access

37

Citations

45

References

2019

Year

Mona El Refaey, Hassan Musa, Nathaniel P. Murphy, Ellen R. Lubbers, Michel Skaf, Mei Han, Omer Cavus, Sara N. Koenig, Michael B. Wallace, Daniel Gratz,
Circulation Research

Abstract

PP2A regulates Na<sub>v</sub>1.5 activity in mouse cardiomyocytes. This regulation is critical for pathogenic Na<sub>v</sub>1.5 late current and requires PP2A-B56α. Our study supports B56α as a novel target for the treatment of arrhythmia.

References

YearCitations

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