Concepedia

Tumor‐infiltrating CD8<sup>+</sup> T‐cell density is an independent prognostic marker for oral squamous cell carcinoma

Shota Shimizu, Hiroyoshi Hiratsuka, Kazushige Koike, Kei Tsuchihashi, Tomoko Sonoda, Kazuhiro Ogi, Akira Miyakawa, Jun’ichi Kobayashi, Takeshi Kaneko, T Igarashi,

Cancer Medicine · 2019 · 170 citations · 34 references

DOIFull text

Open access

Abstract

Assessment of CD8<sup>+</sup> T cells at the parenchyma of the invading edge and peripheral stroma provides an indicator of tumor recurrence and prognosis.

References

34

Human Papillomavirus and Survival of Patients with Oropharyngeal Cancer

K. Kian Ang, Jonathan Harris, Richard Wheeler et al. · New England Journal of Medicine · 2010 · 6.4K citations · Full text

Type, Density, and Location of Immune Cells Within Human Colorectal Tumors Predict Clinical Outcome

Jérôme Galon, Anne Costes, Fátima Sánchez‐Cabo et al. · Science · 2006 · 6.3K citations

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Spatiotemporal Dynamics of Intratumoral Immune Cells Reveal the Immune Landscape in Human Cancer

Gabriela Bindea, Bernhard Mlecnik, Marie Tosolini et al. · Immunity · 2013 · 4.6K citations · Full text

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Intraepithelial CD8<sup>+</sup>tumor-infiltrating lymphocytes and a high CD8<sup>+</sup>/regulatory T cell ratio are associated with favorable prognosis in ovarian cancer

Eiichi Sato, Sara H. Olson, Jiyoung Ahn et al. · Proceedings of the National Academy of Sciences · 2005 · 2.4K citations · Full text

Adaptive immunity maintains occult cancer in an equilibrium state

Catherine Koebel, William Vermi, Jeremy B. Swann et al. · Nature · 2007 · 1.4K citations

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