Preparation, chemical characterization and determination of crocetin's pharmacokinetics after oral and intravenous administration of saffron (<i>Crocus sativus</i> L.) aqueous extract to C57/BL6J mice

Abstract

SFE is a stable lyophilized extract rich in all-trans-crocin. The PK study allowed the estimation of basic PK parameters and the bioavailability of SFE's main bioactive component, crocetin, after peros administration.