The relationship between type 1 IFN and vasculopathy in anti-MDA5 antibody-positive dermatomyositis patients

Abstract

Anti-MDA5 antibody-positive DM patients showed high T1-IFN signatures in serum and affected skin. The high T1-IFN signatures of the MDA5 antibody-positive DM patients in serum and deep vasculatures suggested that T1-IFN may have important roles in the vasculopathy of these patients.