Concepedia

pH and enzyme dual-responsive release of hydrogen sulfide for disc degeneration therapy

Zengming Zheng, Anqi Chen, Huacheng He, Yu Chen, Jian Chen, Abdullkhaleg Ali Albashari, Jiawei Li, Jiayu Yin, Zili He, Qingqing Wang,

Journal of Materials Chemistry B · 2018 · 51 citations · 31 references

DOI

Concepts

Abstract

The collagen hydrogel controllably releases hydrogen sulfide by responding to pH and enzymes for disc degeneration therapy.

References

31

Magnetic Resonance Classification of Lumbar Intervertebral Disc Degeneration

Christian W. A. Pfirrmann, Alexander Metzdorf, Marco Zanetti et al. · Spine · 2001 · 4K citations

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Lost Productive Time and Cost Due to Common Pain Conditions in the US Workforce

Walter F. Stewart · JAMA · 2003 · 1.6K citations

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Hydrogen sulfide attenuates myocardial ischemia-reperfusion injury by preservation of mitochondrial function

John W. Elrod, John W. Calvert, Jo Morrison et al. · Proceedings of the National Academy of Sciences · 2007 · 1.3K citations · Full text

, , +17

Hydrogen Sulfide-Linked Sulfhydration of NF-κB Mediates Its Antiapoptotic Actions

Nilkantha Sen, Bindu D. Paul, Moataz M. Gadalla et al. · Molecular Cell · 2012 · 709 citations · Full text

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Catabolic cytokine expression in degenerate and herniated human intervertebral discs: IL-1β and TNFα expression profile

Christine L. Le Maitre, Judith A. Hoyland, Anthony J. Freemont · Arthritis Research & Therapy · 2007 · 586 citations · Full text

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