Facile synthesis of copper sulfide decorated reduced graphene oxide nanocomposite for high sensitive detection of toxic antibiotic in milk

Abstract

The development of an effective technique for detecting antibiotic drugs remains a serious task due to their toxicity to public health. For this purpose, herein, we report an electrochemical detection based on Cu₂S nanosphere decorated reduced graphene oxide (RGO@Cu₂S NC) nanocomposite. A sonochemical-assisted method was adopted to prepare the nanocomposite. Subsequently, its morphological, elemental, and crystal structural aspects were analysed. The electrochemical properties were examined in order to ensure the material's suitability in electrocatalytic sensing. RGO@Cu₂S NC affixed screen-printed electrode was found to exhibit tremendous electrocatalytic capability toward chloramphenicol (CAP) reduction. A sensitive and reproducible amperometric CAP sensor was fabricated which was able to detect concentration at the nanomolar level. The method worked well even in real samples (fresh milk samples) and the results are evaluated by HPLC method and amperometric methods.