Curcumin Inhibits Proliferation of Synovial Cells by Downregulating Expression of <i>Matrix Metalloproteinase‐3</i> in Osteoarthritis

Abstract

MMP3 was highly expressed in osteoarthritis synovial cells. Curcumin could reduce cell viability, inhibit cell proliferation, increase cell apoptosis, and eventually alleviate inflammation of osteoarthritis by inhibiting the expression of MMP3.