Concepedia

Effects of Chronic Exposure to Mercury on Angiotensin-Converting Enzyme Activity and Oxidative Stress in Normotensive and Hypertensive Rats

Dalton Valentim Vassallo, Maylla Ronacher Simões, Karina Giuberti, Bruna Fernandes Azevedo, Rogério Faustino Ribeiro Júnior, Mercedes Salaíces, Ivanita Stefanon

Arquivos Brasileiros de Cardiologia · 2018 · 22 citations · 32 references

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Abstract

These results suggest that chronic exposure to inorganic mercury aggravates hypertension and produces more expressive changes in ACE activity and oxidative stress in SHRs. Such exposure affects the cardiovascular system, representing a risk factor for the development of cardiovascular disorders in normotensive rats and worsening of pre-existing risks for hypertension.

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