European Journal of Organic Chemistry · 2017 · 16 citations · 22 references
PharmacyPharmaceuticsPharmacologyBiomedical ImagingDrug DeliveryMolecular ImagingDrug Delivery EngineeringDrug Delivery SystemsMagnetic Resonance ImagingMagnetic Resonance SpectroscopyNanomaterials For Drug DeliveryNanoparticle Delivery SystemsDendrimer Drug DeliveryDendrimer-based DeliveryDrug Delivery ImagingDual-modality ImagingMagnetic Drug Delivery SystemsMagnetic Nanoparticle Drug CarriersMagnetic Nanoparticle Drug DeliveryMagnetic Resonance
Monitoring a drug‐delivery system with an imaging modality is of great importance for detailed understanding of drug‐delivery processes and for achieving optimal therapeutic effects. Here, novel fluorinated self‐assembled dendrimers with a single 19 F NMR signal were conveniently synthesized on multigram scales, and 19 F magnetic resonance, including spectroscopy ( 19 F NMR) and imaging ( 19 F MRI), was used to monitor the fluorinated dendrimer‐based self‐assembled drug‐delivery systems. It was found that 19 F NMR and 19 F MRI were convenient and sensitive tools to monitor the self‐assembly and drug‐loading processes and to detect weak interactions between the drug and the drug‐delivery vehicle because changes in the self‐assembly profile sensitively induced corresponding 19 F magnetic resonance responses.
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In vivo imaging platform for tracking immunotherapeutic cells
Eric T. Ahrens, Rafael R. Flores, Hongyan Xu et al. · Nature Biotechnology · 2005 · 614 citations
Medicine, Immunology, Oncology +14
Self-assembly of biodegradable polyurethanes for controlled delivery applications
Mingming Ding, Jiehua Li, Hong Tan et al. · Soft Matter · 2012 · 142 citations