Alterations of Graphic Properties and Related Cognitive Functioning Changes in Mild Alzheimer’s Disease Revealed by Individual Morphological Brain Network

Abstract

< 0.05) in the higher MMSE score zone (28-30), which indicating the potential role of graphic properties in determination of early-stage AD patients. Moreover, the reservations (regions in the occipital and frontal lobes) and alterations (regions in the right temporal lobe and cingulate cortex) of hubs were also detected in the AD patients. Overall, the findings further confirm the selective AD-related disruptions in morphological brain networks and also suggest the feasibility of applying the morphological graphic properties in the discrimination of early-stage AD patients.