miR-494 Sensitizes Gastric Cancer Cells to TRAIL Treatment Through Downregulation of Survivin - Concepedia

Concepedia

Publication | Open Access

miR-494 Sensitizes Gastric Cancer Cells to TRAIL Treatment Through Downregulation of Survivin

DOI Full Paper Access

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References

2018

Year

Shuning Xu, Danyang Li, Tianyuan Li, Lei Qiao, Ke Li, Leiming Guo, Ying Liu

Cellular Physiology and Biochemistry

Abstract

MiR-494/survivin axis represents a potential mechanism which is responsible for TRAIL resistance in gastric cancer cells. Increasing the miR-494 expression may serve as a novel therapeutic strategy to sensitize gastric cancer cells to TRAIL treatment.