Concepedia

F8-IL10: A New Potential Antirheumatic Drug Evaluated by a PET-Guided Translational Approach

Stefan Bruijnen, Durga M. S. H. Chandrupatla, Leonardo Giovanonni, Dario Neri, Daniëlle J. Vugts, Marc C. Huisman, Otto S. Hoekstra, René J.P. Musters, Adriaan A. Lammertsma, Guus A.M.S. van Dongen,

Molecular Pharmaceutics · 2018 · 31 citations · 28 references

DOIFull text

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Concepts

Abstract

I]I-F8-IL10 uptake in the liver and spleen associated with moderate systemic inflammation. This translational study demonstrated the value of in vivo biodistribution and PET-CT-guided imaging in development of new and potential antirheumatic drugs'.

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