Dynorphin-kappa opioid receptor activity in the central amygdala modulates binge-like alcohol drinking in mice

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand

Blaine N. Armbruster, Xiang Li, Mark H. Pausch et al. · Proceedings of the National Academy of Sciences · 2007 · 2.1K citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

Chemogenetics revealed: DREADD occupancy and activation via converted clozapine

Juan L. Gomez, Jordi Bonaventura, Wojciech G. Lesniak et al. · Science · 2017 · 1K citations · Full text

Medicine, Neuroscience, Pharmacology +15

Evaluation of a simple model of ethanol drinking to intoxication in C57BL/6J mice

Justin S. Rhodes, Karyn Best, John K. Belknap et al. · Physiology & Behavior · 2004 · 839 citations

Pharmacy, Pharmacology, Toxicology +10

An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger

Michael J. Krashes, Bhavik P. Shah, Joseph C. Madara et al. · Nature · 2014 · 631 citations · Full text

Life Sciences, Neurobiology, Neuroscience +14

The Short‐Term Effects and Unintended Long‐Term Consequences of Binge Drinking in College: A 10‐Year Follow‐Up Study

Karen M. Jennison · The American Journal of Drug and Alcohol Abuse · 2004 · 412 citations

Public Health, Behavioral Sciences, Psychology +14