Toll-like Receptor 2 Prevents Neutrophil-Driven Immunopathology during Infection with Mycobacterium tuberculosis by Curtailing CXCL5 Production

Archana Gopalakrishnan, Jillian Dietzold, Sheetal Verma, Madhuri Bhagavathula, Padmini Salgame

Infection and Immunity · 2018 · 20 citations · 36 references

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Abstract

The W-Beijing strain family is globally distributed and is associated with multidrug-resistant tuberculosis (TB) and treatment failure. Therefore, in this study, we examined the contribution of Toll-like receptor 2 (TLR2) to host resistance against Mycobacterium tuberculosis HN878, a clinical isolate belonging to the W-Beijing family.

References

36