Concepedia

Brain GABA levels are reduced in alcoholic liver disease: A proton magnetic resonance spectroscopy study

Kirsten C. Morley, Jim Lagopoulos, Warren Logge, Andrew Baillie, Claire Adams, Paul Haber

Addiction Biology · 2018 · 16 citations · 14 references

DOI

Abstract

Severity of ALD is associated with lower cortical concentrations of GABA+. These results may explain variations in response to the GABA<sub>B</sub> agonist, baclofen, in the alcohol-dependent population.

References

14

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Effectiveness and safety of baclofen for maintenance of alcohol abstinence in alcohol-dependent patients with liver cirrhosis: randomised, double-blind controlled study

Giovanni Addolorato, Lorenzo Leggio, Anna Ferrulli et al. · The Lancet · 2007 · 666 citations

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