Assessing seizure liability using multi-electrode arrays (MEA)

Bicuculline and Gabazine Are Allosteric Inhibitors of Channel Opening of the GABA_AReceptor

Shinya Ueno, John Bracamontes, Chuck Zorumski et al. · Journal of Neuroscience · 1997 · 262 citations · Full text

Medicine, Neuroscience, Pharmacology +17

Convulsant potencies of tetrazoles are highly correlated with actions on GABA/benzodiazepine/picrotoxin receptor complexes in brain

Richard F. Squires, Else Saederup, Jacqueline N. Crawley et al. · Life Sciences · 1984 · 200 citations

Life Sciences, Neuroscience, Pharmacology +14

Seizures and neurodegeneration induced by 4-aminopyridine in rat hippocampus in vivo: role of glutamate- and GABA-mediated neurotransmission and of ion channels

Ricardo Tapia · Neuroscience · 2000 · 195 citations

Life Sciences, Neurobiology, Neuroscience +16

Kinetics of drug action in disease states. XIV. Effect of infusion rate on pentylenetetrazol concentrations in serum, brain and cerebrospinal fluid of rats at onset of convulsions.

Iqbal Ramzan, G Lévy · Journal of Pharmacology and Experimental Therapeutics · 1985 · 88 citations

Medicine, Pharmacokinetics, Pharmacology +15

Electrophysiological recording of re-aggregating brain cell cultures on multi-electrode arrays to detect acute neurotoxic effects

Luc Stoppini, Maurizio Balestrino, Chantra Eskes et al. · NeuroToxicology · 2007 · 80 citations

Life Sciences, Neurobiology, Neuroscience +15