Concepedia

The bacterial lipid II flippase MurJ functions by an alternating-access mechanism

Sujeet Kumar, Frederick A. Rubino, Alicia G. Mendoza, Natividad Ruiz

Journal of Biological Chemistry · 2018 · 49 citations · 31 references

DOIFull text

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Concepts

Abstract

evidence that MurJ uses an alternating-access mechanism during the lipid II transport cycle.

References

31

Identification of a protein complex that assembles lipopolysaccharide in the outer membrane of <i>Escherichia coli</i>

Tao Wu, Andrew C. McCandlish, Luisa S. Gronenberg et al. · Proceedings of the National Academy of Sciences · 2006 · 366 citations · Full text

, , +12

MurJ is the flippase of lipid-linked precursors for peptidoglycan biogenesis

Lok‐To Sham, Emily K. Butler, Matthew D. Lebar et al. · Science · 2014 · 333 citations · Full text

, , +17

Structure of a cation-bound multidrug and toxic compound extrusion transporter

Xiao He, Paul Szewczyk, Andrey Karyakin et al. · Nature · 2010 · 274 citations · Full text

, , +10

Structural basis for the drug extrusion mechanism by a MATE multidrug transporter

Yoshiki Tanaka, Christopher J. Hipolito, Andrés D. Maturana et al. · Nature · 2013 · 257 citations · Full text

, , +9

Electrogenic properties of the cloned Na+/glucose cotransporter: I. Voltage-clamp studies

Lucie Parent, Stéphane Supplisson, DonaldD.F. Loo et al. · The Journal of Membrane Biology · 1992 · 251 citations

, , +9