Concepedia

Characterisation of the biosynthetic pathway to agnestins A and B reveals the reductive route to chrysophanol in fungi

Agnieszka J. Szwalbe, Katherine Williams, Zhongshu Song, Kate M. J. de Mattos-Shipley, Andy M. Bailey, Christine L. Willis, Russell J. Cox, Thomas J. Simpson

Chemical Science · 2018 · 58 citations · 35 references

DOIFull text

Open access

Concepts

Abstract

Identification of a reductase (AgnL4) confirms that<italic>in vivo</italic>anthraquinone to anthrol conversion is an essential first step in aromatic deoxygenation of anthraquinones catalysed by AgnL6 (reductase) and AgnL8 (dehydratase).

References

35

WET, a T1- and B1-Insensitive Water-Suppression Method for in Vivo Localized 1H NMR Spectroscopy

Robert J. Ogg, R.B. Kingsley, J S Taylor · Journal of Magnetic Resonance Series B · 1994 · 726 citations

, , +5

Loss of ETHE1, a mitochondrial dioxygenase, causes fatal sulfide toxicity in ethylmalonic encephalopathy

Valeria Tiranti, Carlo Viscomi, Tatjana M. Hildebrandt et al. · Nature Medicine · 2009 · 409 citations

, , +16

Molecular characterization of aflR, a regulatory locus for aflatoxin biosynthesis

Charles P. Woloshuk, Kirk R. Foutz, J. F. Brewer et al. · Applied and Environmental Microbiology · 1994 · 323 citations · Full text

, , +12

Characterization of the <i>Aspergillus nidulans</i> Monodictyphenone Gene Cluster

Yi‐Ming Chiang, Edyta Szewczyk, Ashley D. Davidson et al. · Applied and Environmental Microbiology · 2010 · 212 citations · Full text

, , +17

Genome-Based Deletion Analysis Reveals the Prenyl Xanthone Biosynthesis Pathway in <i>Aspergillus nidulans</i>

James F. Sanchez, Ruth Entwistle, Jui‐Hsiang Hung et al. · Journal of the American Chemical Society · 2011 · 181 citations · Full text

, , +17