Cannabinoid CB2 Agonist AM1710 Differentially Suppresses Distinct Pathological Pain States and Attenuates Morphine Tolerance and Withdrawal

Ethical guidelines for investigations of experimental pain in conscious animals

M. Zimmermann · Pain · 1983 · 7.8K citations

Medicine, Anesthesiology, Animal Sciences +14

Characterization and localization of cannabinoid receptors in rat brain: a quantitative in vitro autoradiographic study

Miles Herkenham, A B Lynn, MR Johnson et al. · Journal of Neuroscience · 1991 · 2.2K citations · Full text

Medicine, Neuroscience, Pharmacology +14

Expression of Central and Peripheral Cannabinoid Receptors in Human Immune Tissues and Leukocyte Subpopulations

Sylvaine Galiègue, Sophie Mary, Jean Marchand et al. · European Journal of Biochemistry · 1995 · 1.8K citations · Full text

Life Sciences, Immunology, Neurobiology +7

μ-Opioid receptor desensitization by β-arrestin-2 determines morphine tolerance but not dependence

Laura Bohn, Raul R. Gainetdinov, Fang‐Tsyr Lin et al. · Nature · 2000 · 916 citations

Medicine, Neuroscience, Pharmacology +14

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

Christian C. Felder, Kelly E. Joyce, Eileen M. Briley et al. · Molecular Pharmacology · 1995 · 879 citations

Medicine, Pharmacology, Cell Signaling +7