High frequency of mutations in <i>gyrA</i> gene associated with quinolones resistance in uropathogenic <i>Escherichia</i> <i>coli</i> isolates from the north of Iran.

Abstract

Our results revealed a high level of quinolone resistance associated with the mutations in <i>gyrA</i> among the clinical isolates of UPEC in our region. To the best of our knowledge, this study is the first investigation on the role of <i>gyrA</i> alteration in quinolone resistance among UPEC isolates from the north of Iran.