Clinical Infectious Diseases · 2018 · 38 citations · 8 references
PharmacyClinical PharmacyHospital PharmacyAntimicrobial PharmacotherapyAntimicrobial StewardshipAntibiotic ResistanceAntibiotic Time-outsAntimicrobial Stewardship ReviewAntimicrobial Utilization ReviewHospital Antimicrobial StewardshipAntibiotic Prescribing Decision SupportAntibiotic Utilization MeasurementDelayed Antibiotic PrescribingRational Antibiotic UseStewardship Intervention ImplementationStructured Time-out ChecklistsTime-to-antibiotic Initiation
A multicenter quasi-experimental study of a provider-driven antibiotic "time-out" in 3470 antibiotic courses showed no difference in antibiotic use before and after implementation, but did show a decrease in inappropriate therapy (45% vs 31%, P < .05). Single time-outs without input from antibiotic stewardship teams are insufficient to optimize prescribing.
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Sara E. Cosgrove, Susan K. Seo, Maureen Bolon et al. · Infection Control and Hospital Epidemiology · 2012 · 96 citations