Knockdown of Long Noncoding RNA HOXA-AS2 Suppresses Chemoresistance of Acute Myeloid Leukemia via the miR-520c-3p/S100A4 Axis - Concepedia

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Knockdown of Long Noncoding RNA HOXA-AS2 Suppresses Chemoresistance of Acute Myeloid Leukemia via the miR-520c-3p/S100A4 Axis

DOI Full Paper Access

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References

2018

Year

Xiaoya Dong, Zhigang Fang, Mingxue Yu, Ling Zhang, Ruozhi Xiao, Xudong Li, Guangjin Pan, Jiajun Liu

Cellular Physiology and Biochemistry

Abstract

Our results suggest that HOXA-AS2 plays an important role in the resistance of AML cells to adriamycin. Thus, HOXA-AS2 may represent a therapeutic target for overcoming resistance to adriamycin-based chemotherapy in AML.