Synthesis of azabicyclo[n.1.0]alkane-derived bifunctional building blocks via the Corey–Chaykovsky cyclopropanation

Discovery and Preclinical Profile of Saxagliptin (BMS-477118):  A Highly Potent, Long-Acting, Orally Active Dipeptidyl Peptidase IV Inhibitor for the Treatment of Type 2 Diabetes

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Pharmacy, Medicinal Chemistry, Pharmacology +10

Recent progress on the stereoselective synthesis of cyclic quaternary α-amino acids

Carlos Cativiela, Mario Ordóñez · Tetrahedron Asymmetry · 2009 · 276 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +13

Rhodium(I)-Catalyzed Cycloisomerizations of Bicyclobutanes

Maciej A. Walczak, Peter Wipf · Journal of the American Chemical Society · 2008 · 104 citations · Full text

Natural Sciences, Chemistry, Medicinal Chemistry +12

Synthesis of Novel Potent Dipeptidyl Peptidase IV Inhibitors with Enhanced Chemical Stability:  Interplay between the N-Terminal Amino Acid Alkyl Side Chain and the Cyclopropyl Group of α-Aminoacyl-<scp>l</scp>-<i>cis</i>-4,5-methanoprolinenitrile-Based Inhibitors

David R. Magnin, Jeffrey A. Robl, Richard Sulsky et al. · Journal of Medicinal Chemistry · 2004 · 103 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +11

Dual Catalysis: Proton/Metal-Catalyzed Tandem Benzofuran Annulation/Carbene Transfer Reaction

Jun Ma, Kai Chen, Hong–Guang Fu et al. · Organic Letters · 2016 · 95 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17