Concepedia

Glucose negatively affects Nrf2/SKN-1-mediated innate immunity in C. elegans

Le Li, Yi Chen, Changchi Chenzhao, Shuxiang Fu, Qumiao Xu, Jinfeng Zhao

Aging · 2018 · 27 citations · 28 references

DOIFull text

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Abstract

. In all, our study reveals a molecular pathway responsible for glucose's negative effect on innate immunity, which could help to better understand diseases associated with hyperglycemia.

References

28

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Glucose Restriction Extends Caenorhabditis elegans Life Span by Inducing Mitochondrial Respiration and Increasing Oxidative Stress

Tim J. Schulz, Kim Zarse, Anja Voigt et al. · Cell Metabolism · 2007 · 1.2K citations · Full text

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Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis

Rajesh K. Thimmulappa · Journal of Clinical Investigation · 2006 · 1K citations · Full text

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Complementary Signaling Pathways Regulate the Unfolded Protein Response and Are Required for C. elegans Development

Xiaohua Shen, Ronald Ellis, Kyung‐Ho Lee et al. · Cell · 2001 · 715 citations · Full text

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Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones

Takunari Yoneda, Cristina Benedetti, Fumihiko Urano et al. · Journal of Cell Science · 2004 · 670 citations

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