AgBF₄-catalyzed deoxygenative C2-amination of quinoline <i>N</i>-oxides with isothiocyanates

Abstract

A general, effective and convenient protocol for the direct synthesis of various 2-aminoquinolines (39 examples) through AgBF₄-catalyzed amination of quinoline <italic>N</italic>-oxides with isothiocyanates under base-, oxidant-free and mild conditions was developed.