Nanomedicine · 2018 · 14 citations · 9 references
MedicineOncologyRadiologyBiomedical ImagingBreast OncologyDiagnostic ImagingBreast Cancer SurgeryBreast SurgeryCancer DetectionSentinel Lymph Node BiopsySentinel Lymph Node MappingTumor DetectionBreast Cancer Sentinel Node MappingIntraoperative Sentinel Node DetectionNanoparticlesNegative Surgical MarginsNonpalpable Breast Lesion LocalizationSentinel Lymph Node IdentificationSentinel NodesSurgical Resection Margins
AIM: In this study we used a new technology for localization of non-palpable breast tumors using a small steel marker in conjunction of sentinel nodes (SLNs) detection through injection of SPIO nanoparticles; both detected through a magnetic probe. Materials & methods: Ten patients with biopsy-proven nonpalpable invasive breast carcinoma or premalignant lesions eligible for SLNs biopsy were enrolled in this study. RESULTS: All tumors were removed with safe surgical margins. The mean nodal detection rate was 3.4 nodes per patient. No interferences in magnetic probe measurements due to the presence of both markers in the same breast were observed. CONCLUSION: Simultaneous use of the magnetic method in localization of impalpable breast tumors and SNs detection makes breast surgery convenient.
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Andreas Karakatsanis, Peer Christiansen, Lone Fischer et al. · Breast Cancer Research and Treatment · 2016 · 143 citations · Full text
Medicine, Nuclear Medicine, Oncology +17
Isabel T. Rubio, Sebastian Díaz-Botero, Antonio Esgueva et al. · European Journal of Surgical Oncology · 2014 · 140 citations