T-Cell Receptor Rearrangements Determined Using Fragment Analysis in Patients With T-Acute Lymphoblastic Leukemia

Abstract

BACKGROUND: clonality, and feasibility for detecting minimal residual disease (MRD). METHODS: clonality was examind by age and immunophenotypic classification. RESULTS: clonality. The LOD was 1%. Clonal evolution at the relapse period was noted. CONCLUSIONS: rearrangements is needed, using more sensitive methods to detect clonality and monitor MRD.