Facile synthesis of 1,4-benzodiazepine-2,5-diones and quinazolinones from amino acids as anti-tubercular agents

Abstract

A family of 1,4-benzodiazepine-2,5-diones and quinazolinones with diverse substituents at C-3 position are synthesized by novel, simple and convenient methodology using H₂PtCl₆as catalyst and were all screened for anti-TB activity.