Concepedia

Pancreatic stellate cells derived from human pancreatic cancer demonstrate aberrant SPARC-dependent ECM remodeling in 3D engineered fibrotic tissue of clinically relevant thickness

Hiroyoshi Tanaka, Kentaro Kitahara, Naoki Sasaki, Natsumi Nakao, Kae Sato, Hirokazu Narita, Hiroshi Shimoda, Michiya Matsusaki, Hiroshi Nishihara, Atsushi Masamune,

Biomaterials · 2018 · 45 citations · 62 references

DOIFull text

Open access

Concepts

References

62

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson et al. · Science · 2009 · 3.1K citations · Full text

, , +17

Depletion of Carcinoma-Associated Fibroblasts and Fibrosis Induces Immunosuppression and Accelerates Pancreas Cancer with Reduced Survival

Berna C. Özdemir, Tsvetelina Pentcheva‐Hoang, Julienne L. Carstens et al. · Cancer Cell · 2014 · 2.6K citations

, , +15

Virtual microdissection identifies distinct tumor- and stroma-specific subtypes of pancreatic ductal adenocarcinoma

Richard A. Moffitt, Raoud Marayati, Elizabeth L. Flate et al. · Nature Genetics · 2015 · 2.2K citations · Full text

, , +14

Organoid Models of Human and Mouse Ductal Pancreatic Cancer

Sylvia F. Boj, Chang‐Il Hwang, Lindsey A. Baker et al. · Cell · 2014 · 2.2K citations · Full text

, , +14

Enzymatic Targeting of the Stroma Ablates Physical Barriers to Treatment of Pancreatic Ductal Adenocarcinoma

Paolo P. Provenzano, Carlos Cuevas, Amy Chang et al. · Cancer Cell · 2012 · 2.1K citations · Full text

, , +14