Screening system for epidermal growth factor receptor mutation detection in cytology cell‐free <scp>DNA</scp> of cerebrospinal fluid based on assured sample quality

Abstract

The cobas^® EGFR Mutation Test v2.0 can accurately detect EGFR mutations, including T790M, from supernatant cfDNA of CSF cytology samples. Utilisation of supernatant cytology cfDNA in CSF will allow us to perform both EGFR mutation analysis and cytopathological diagnosis at the same time. This represents a new role of cytology in patient treatment, based on assured sample quality.