Better science for safer medicines: the human imperative

Genomic responses in mouse models poorly mimic human inflammatory diseases

Junhee Seok, H. Shaw Warren, Alex G. Cuenca et al. · Proceedings of the National Academy of Sciences · 2013 · 3K citations · Full text

Veterinary Medicine, Immunology, Molecular Genetics +17

The multi-level perspective on sustainability transitions: Responses to seven criticisms

Frank W. Geels · Environmental Innovation and Societal Transitions · 2011 · 2.9K citations · Full text

Natural Sciences, Environmental Policy, Sustainability Management +13

Cellular Imaging Predictions of Clinical Drug-Induced Liver Injury

Jinghai J. Xu, Peter Henstock, Margaret C. Dunn et al. · Toxicological Sciences · 2008 · 492 citations · Full text

Pharmacy, Pharmacology, Toxicology +17

Why clinical trial outcomes fail to translate into benefits for patients

Carl Heneghan, Ben Goldacre, Kamal R Mahtani · Trials · 2017 · 424 citations · Full text

Pharmacy, Pharmacoeconomics, Evidence-based Practice +16

Real-time monitoring of metabolic function in liver-on-chip microdevices tracks the dynamics of mitochondrial dysfunction

Danny Bavli, Sebastian Prill, Elishai Ezra Tsur et al. · Proceedings of the National Academy of Sciences · 2016 · 349 citations · Full text

Life Sciences, Bioengineering, Cell Biology +17