Posterior reversible encephalopathy syndrome during treatment with tocilizumab in juvenile idiopathic arthritis

Abstract

A 17-year-old man with normal blood pressure presented with acute bilateral blindness, and retro-orbital pain two days after treatment with tocilizumab (TCZ) for juvenile idiopathic arthritis. The diagnosis was posterior reversible encephalopathy syndrome (PRES), made after clinical examination and MRI (Figure ).