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Reliable and easy-to-use LC–MS/MS-method for simultaneous determination of the antihypertensives metoprolol, amlodipine, canrenone and hydrochlorothiazide in patients with therapy-refractory arterial hypertension

HypertensionCardiovascular DiseaseTherapy-refractory Arterial HypertensionAntihypertensive TherapyPharmacologyBlood Pressure ControlEasy-to-use Lc–ms/ms-methodSimultaneous DeterminationMedicineBlood Pressure