Molecular cloning of the human CTP synthetase gene by functional complementation with purified human metaphase chromosomes.

Point mutations define a sequence flanking the AUG initiator codon that modulates translation by eukaryotic ribosomes

Marilyn Kozak · Cell · 1986 · 4.9K citations

Life Sciences, Genetics, Molecular Biology +14

Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer.

Michael A. Frohman, Michael Dush, Gail R. Martin · Proceedings of the National Academy of Sciences · 1988 · 4.6K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +13

Molecular cloning of human uracil‐DNA glycosylase, a highly conserved DNA repair enzyme.

Lisbeth C. Olsen, Rein Aasland, Christian Urs Wittwer et al. · The EMBO Journal · 1989 · 185 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

Spontaneous deletion formation at the aprt locus of hamster cells: the presence of short sequence homologies and dyad symmetries at deletion termini.

Joséphine Nalbantoglu, David A. Hartley, Geraldine Phear et al. · The EMBO Journal · 1986 · 158 citations

Medicine, Genetics, Molecular Genetics +9

Isolation and characterization of expressible cDNA clones encoding the M1 and M2 subunits of mouse ribonucleotide reductase.

Lars Thelander, Paul Berg · Molecular and Cellular Biology · 1986 · 149 citations

Life Sciences, Biochemistry, Molecular Biology +8