Mass spectrometry imaging of the in situ drug release from nanocarriers

Jinjuan Xue, Huihui Liu, Suming Chen, Caiqiao Xiong, Lingpeng Zhan, Jie Sun, Zongxiu Nie

Science Advances · 2018 · 94 citations · 23 references

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Concepts

Abstract

nanocarriers are predominantly distributed in lung, spleen, and liver tissues, whereas the accumulation in the tumor was unexpectedly lower than in normal tissues. This new strategy could also be extended to other drug-carrier systems, such as carbon nanotubes and black phosphorus nanosheets, and opened a new path to evaluate the drug release of nanocarriers in the suborgan level.

References

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