Rational synthesis of hollow cubic CuS@Spiky Au core–shell nanoparticles for enhanced photothermal and SERS effects

Abstract

Hollow cubic CuS@Spiky Au core-shell nanoparticles (NPs) were rationally synthesized both for guided highly efficient damage to cancer cells by the photothermal effect and for the real-time monitoring of biochemical responses during cellular apoptosis, totally based on label-free SERS intracellular imaging.