Concepedia

Publication | Open Access

Direct therapeutic targeting of immune checkpoint PD-1 in pancreatic cancer

DOIFull Paper Access

54

Citations

35

References

2018

Year

Mei Gao, Miranda Lin, Richard A. Moffitt, Marcela A. Salazar, Jinha Park, Jeffrey Vacirca, Chuan Huang, Kenneth R. Shroyer, Minsig Choi, Georgios Georgakis,
British Journal of Cancer

Abstract

Our data reveal PCs innately express PD-1 and activate druggable oncogenic pathways supporting PDAC growth. Strategies directly targeting PC with novel ICI regimens may work with adaptive immune responses for optimal cytotoxicity.

References

YearCitations

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