Stearyl polyethylenimine complexed with plasmids as the core of human serum albumin nanoparticles noncovalently bound to CRISPR/Cas9 plasmids or siRNA for disrupting or silencing PD-L1 expression for immunotherapy

Abstract

The plasmids/<i>st</i>PEI/HSA NPs could be a promising tool for gene delivery and improved immunotherapy.