Differential expression of periostin, sclerostin, receptor activator of nuclear factor‐κB, and receptor activator of nuclear factor‐κB ligand genes in severe chronic periodontitis

Abstract

The expression profile of SOST, RANK, RANKL, and POSTN genes observed in gingival tissue samples from sites with severe chronic periodontitis and healthy gingiva suggests that the differential level of the gene expression could serve as an indicator of periodontitis progression/severity.